Variability in Total Brain Volume

 
   Lead Investigator:    Shana Stites
   Institution      :    University of Pennsylvania
   E-Mail           :    stites@pennmedicine.upenn.edu
   Proposal ID      :    1259



   Proposal Description:
   Examine and describe the distribution of total brain volume in UDS participants. I plan to conduct descriptive analyses of the distribution of intracranial volume (ICV) in the sample stratified by gender/sex. As available in the data, I will examine the association between ICV and sex in study groups defined by age and Alzheimer?s disease biomarkers (amyloid, tau, and neurodegeneration). Results may be used as pilot data to support development of a new project to study biologic sex in preclinical AD.